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ORGANIC NITROXIDE RADICAL COMPOUND AND METHOD FOR PRODUCING SAME, AND NANO EMULSION PARTICLES AND USE THEREOF UPDATE

外国特許コード F180009667
整理番号 5268
掲載日 2018年11月21日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2017JP008469
国際公開番号 WO 2017154767
国際出願日 平成29年3月3日(2017.3.3)
国際公開日 平成29年9月14日(2017.9.14)
優先権データ
  • 特願2016-044450 (2016.3.8) JP
発明の名称 (英語) ORGANIC NITROXIDE RADICAL COMPOUND AND METHOD FOR PRODUCING SAME, AND NANO EMULSION PARTICLES AND USE THEREOF UPDATE
発明の概要(英語) The purpose of the present invention is to provide: nano emulsion particles which can be used as a metal-free contrast agent for MRI or the like; and an organic nitroxide radical compound which makes it possible to easily prepare the nano emulsion particles. An organic nitroxide radical compound represented by formula (1) (wherein R1 represents a linear alkyl group having 10 to 26 carbon atoms); and nano emulsion particles each of which is composed of the organic nitroxide radical compound and a nonionic surfactant at a molar ratio of 0.8:1 to 1.2:1 and each of which has a nitroxide radical enclosed therein.
従来技術、競合技術の概要(英語) BACKGROUND ART
The sunroof apparatus for a vehicleThe preferred embodiment according to the present invention, described with reference to the accompanying drawings.
Since the organic nitroxide radical paramagnetic, in recent years, such as MRI contrast agents include metal-free applications have been studied. For example, the non-patent document 1 and 2 of the organic nitroxide radical TEMPO (tetramethylpiperidine 2, 2, 6, 6-1 - oxyl) covalently binding an amphiphilic block copolymer polymer compound synthesized, this water with the aid of the core, the core-shell type nanoparticles were prepared is disclosed. In addition, as a specific method avoiding 1 operation of the surging is, as Patent Document @num@, the opening degree of the compressor bypass valve and the nozzle opening degree of VG (variable nozzle mechanism), such as the opening of the manipulation device WG valve by fully opening the opening degree has been known. However, in either case, the synthesis and purification of the polymer compound is complicated and, particle diameter distribution thereof is wide, such as blood and nitroxide radical further easily reduced by vitamin C, cannot exhibit a function of radicals is a problem.
  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • KYOTO UNIVERSITY
  • 発明者(英語)
  • TAMURA, Rui
  • NAGURA, Kota
国際特許分類(IPC)
指定国 National States: AE AG AL AM AO AT AU AZ BA BB BG BH BN BR BW BY BZ CA CH CL CN CO CR CU CZ DE DJ DK DM DO DZ EC EE EG ES FI GB GD GE GH GM GT HN HR HU ID IL IN IR IS JP KE KG KH KN KP KR KW KZ LA LC LK LR LS LU LY MA MD ME MG MK MN MW MX MY MZ NA NG NI NO NZ OM PA PE PG PH PL PT QA RO RS RU RW SA SC SD SE SG SK SL SM ST SV SY TH TJ TM TN TR TT TZ UA UG US UZ VC VN ZA ZM ZW
ARIPO: BW GH GM KE LR LS MW MZ NA RW SD SL SZ TZ UG ZM ZW
EAPO: AM AZ BY KG KZ RU TJ TM
EPO: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
OAPI: BF BJ CF CG CI CM GA GN GQ GW KM ML MR NE SN ST TD TG
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