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ANTI-GPC-1 ANTIBODY NEW

外国特許コード F190009685
整理番号 (S2017-0686-N0)
掲載日 2019年1月23日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2018JP017291
国際公開番号 WO 2018199318
国際出願日 平成30年4月27日(2018.4.27)
国際公開日 平成30年11月1日(2018.11.1)
優先権データ
  • 特願2017-090054 (2017.4.28) JP
発明の名称 (英語) ANTI-GPC-1 ANTIBODY NEW
発明の概要(英語) Provided is a novel anti-Glypican-1 antibody and a method for using the same. Provided is an anti-Glypican-1 antibody having an intracellular migration activity which has never been observed in conventional anti-Glypican-1 antibodies. By taking advantage of the intracellular migration activity of the antibody according to the present invention, the present invention is usable for various therapeutic purposes beyond the scope of the conventional assumption. Also provided is a composition for preventing or treating Glypican-1 positive cancer, said composition comprising a complex of a substance capable of binding to Glypican-1 (for example, an anti-Glypican-1 antibody) with a drug having a cytotoxic activity.
従来技術、競合技術の概要(英語) BACKGROUND ART
Glypican-1 molecules, than normal cells strongly expressed in esophageal cancer cells and significantly, can be used as a tumor marker has been found (Patent Document 1).Further, an antibody that binds specifically to Glypican-1 also been isolated (Patent Document 1).However, effectively targeting Glypican-1 therapeutic agent has not been found.
  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • NATIONAL UNIVERSITY CORPORATION KOCHI UNIVERSITY
  • 発明者(英語)
  • NAKA Tetsuji
  • SERADA Satoshi
  • FUJIMOTO Minoru
国際特許分類(IPC)
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