Top > Search of International Patents > THERAPEUTIC DRUG FOR DISEASES MAINLY INVOLVING TENOSYNOVIAL LESIONS

THERAPEUTIC DRUG FOR DISEASES MAINLY INVOLVING TENOSYNOVIAL LESIONS commons

Foreign code F190009730
File No. NU-684
Posted date Apr 2, 2019
Country WIPO
International application number 2018JP047135
International publication number WO 2019135363
Date of international filing Dec 21, 2018
Date of international publication Jul 11, 2019
Priority data
  • P2018-000898 (Jan 7, 2018) JP
Title THERAPEUTIC DRUG FOR DISEASES MAINLY INVOLVING TENOSYNOVIAL LESIONS commons
Abstract The purpose of the present invention is to provide an effective therapeutic drug for various pathoses mainly involving tenosynovial lesions. Provided is a therapeutic drug comprising, as an active ingredient, tranilast or a pharmaceutically acceptable salt thereof.
Outline of related art and contending technology BACKGROUND ART
Is mainly to aid paratendinitis disease lesion. And the administration of the steroid treatment to aid surgical procedure is performed (operation), a sufficient effect is not obtained in some cases, a high probability of relapse. In addition, the control of blood glucose in diabetic patients affected by the, administration of the steroid agents needs to be performed carefully.
On the other hand, carpal tunnel syndrome is the numbness and pain of the fingers, such as muscle weakness kitashi, QOL (quality of life) of the patient to a disease is seriously impaired, in a typical histological findings, thickening of the tendon around the carpal by connective tissue to increase the inner pressure can be said to be a fault occurs in the median. To aid in the carpal tunnel syndrome often be combined, in this case, particularly the treatment becomes difficult. Incidentally, due to limited effect of the drug therapy, current, carpal surgical therapy is generally a set of symptoms often done, and the burden on the patient.
Scope of claims (In Japanese)[請求項1]
 トラニラスト又はその薬学的に許容される塩を有効成分として含有する、腱滑膜病変を主体とした疾患の治療薬。

[請求項2]
 前記疾患が腱鞘炎である、請求項1に記載の治療薬。

[請求項3]
 前記疾患がばね指、ドケルバン腱鞘炎、インターセクション症候群、前・後脛骨筋腱鞘炎又は足趾腱鞘炎である、請求項1に記載の治療薬。

[請求項4]
 手根管症候群に腱鞘炎を合併した患者に投与されることを特徴とする、請求項1に記載の治療薬。

[請求項5]
 前記疾患を罹患した糖尿病患者に投与されることを特徴とする、請求項1~4のいずれか一項に記載の治療薬。

[請求項6]
 腱滑膜病変を主体とした疾患を罹患した患者に対して、治療上有効量のトラニラスト又はその薬学的に許容される塩を投与する治療法。
  • Applicant
  • ※All designated countries except for US in the data before July 2012
  • NAGOYA UNIVERSITY
  • Inventor
  • HIRATA Hitoshi
  • KAWAMOTO Hiroya
  • IWATSUKI Katsuyuki
IPC(International Patent Classification)
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