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NANOPARTICLE, NANOPARTICLE PRODUCTION METHOD, AND ANTI-TUMOR AGENT 新技術説明会

外国特許コード F190009732
整理番号 17061
掲載日 2019年4月19日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2019JP008494
国際公開番号 WO 2019172213
国際出願日 平成31年3月5日(2019.3.5)
国際公開日 令和元年9月12日(2019.9.12)
優先権データ
  • 特願2018-038989 (2018.3.5) JP
発明の名称 (英語) NANOPARTICLE, NANOPARTICLE PRODUCTION METHOD, AND ANTI-TUMOR AGENT 新技術説明会
発明の概要(英語) This nanoparticle (1) has a core (10) of MFe2O4 (where M represents a transition metal) and a shell (20) covering the core (10). The shell (20) is chemically modified with glucose or a glucose derivative Glc'. X is a divalent linking group. The nanoparticle (1) can be produced by the steps of: forming a core-shell-type nanoparticle having a core (10) of MFe2O4 and a shell having a functional group covering the core (10); and reacting glucose or a glucose derivative with the functional group.
従来技術、競合技術の概要(英語) BACKGROUND ART
Nano-particles are ultra fine particles of nanometer scale, resulting in a new specific non-conventional properties, the performance of the functional material can be expected, has been studied a variety of substances. In particular, fine particles of the magnetic material, no domain walls occur in the single domain particles, the coercive force is expected to increase.
The inventors of the present invention, magnetite SiO2 surface covered by the preparation of magnetic nano-particles and succeeded, the SiO2 techniques to introduce the functional group via reported (Patent Document 1, reference 2). The functional groups, such as a drug to and modification of the magnetic fine particles, cells, the magnetic fine particles into the tissue can be easily taken.
On the other hand, the cancer cells may be normal cells per unit time of 3-8 times compared with the known capture glucose. Also, EPR effect, that is, the vessel wall around the cancer cells easily permeate through the polymer agent, the polymer agent is transmitted in the tumor tissue can be easily integrated or in the periphery thereof which are also known.
  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • YOKOHAMA NATIONAL UNIVERSITY
  • SAITAMA MEDICAL UNIVERSITY
  • NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGY
  • OSAKA UNIVERSITY
  • 発明者(英語)
  • ICHIYANAGI Yuko
  • HASHIMOTO Tatsuya
  • SENBONMATSU Takaaki
  • TANAKA Shukichi
  • ABE Masayuki
国際特許分類(IPC)
指定国 National States: AE AG AL AM AO AT AU AZ BA BB BG BH BN BR BW BY BZ CA CH CL CN CO CR CU CZ DE DJ DK DM DO DZ EC EE EG ES FI GB GD GE GH GM GT HN HR HU ID IL IN IR IS JO JP KE KG KH KN KP KR KW KZ LA LC LK LR LS LU LY MA MD ME MG MK MN MW MX MY MZ NA NG NI NO NZ OM PA PE PG PH PL PT QA RO RS RU RW SA SC SD SE SG SK SL SM ST SV SY TH TJ TM TN TR TT TZ UA UG US UZ VC VN ZA ZM ZW
ARIPO: BW GH GM KE LR LS MW MZ NA RW SD SL SZ TZ UG ZM ZW
EAPO: AM AZ BY KG KZ RU TJ TM
EPO: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
OAPI: BF BJ CF CG CI CM GA GN GQ GW KM ML MR NE SN ST TD TG
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