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PROTEINS NECTIN-3

Foreign code	F040000976
File No.	(E041P22)
Posted date	Apr 25, 2005
Country	WIPO
International application number	2001JP001871
International publication number	WO 2001066736
Date of international filing	Mar 9, 2001
Date of international publication	Sep 13, 2001
Priority data	P2000-065595 (Mar 9, 2000) JP
Title	PROTEINS NECTIN-3
Abstract	Proteins nectin-3 having the amino acid sequences represented by SEQ ID NOS:2, 4 and 6 which are novel proteins belonging to the nectin protein family participating in the adhesion between cells; polynucleotides encoding these proteins nectin-3 and having the base sequences respectively represented by SEQ ID NOS:1, 3 and 5; recombinant vectors having these polynucleotides; and antibodies against the above-described proteins nectin-3. The proteins nectin-3 not only provide important information in clarifying the whole molecular mechanism of cell adhesion but potentially relate to the clarification of, for example, the infiltration and metastasis mechanisms of cancer, thereby being useful in diagnosing the malignancy of cancer, developing methods of preventing and treating the same and remedies, etc. therefor.
Scope of claims	(In Japanese)1．　配列番号2のアミノ酸配列を有する蛋白質ネクチン－3。 2．　配列番号4のアミノ酸配列を有する蛋白質ネクチン－3。 3．　配列番号6のアミノ酸配列を有する蛋白質ネクチン－3。 4．　請求項1から3のいずれかの蛋白質ネクチン－3をコードするポリヌクレオチド。 5．　配列番号1の塩基配列を有する請求項2のポリヌクレオチド。 6．　配列番号3の塩基配列を有する請求項2のポリヌクレオチド。 7．　配列番号5の塩基配列を有する請求項2のポリヌクレオチド。 8．　請求項4から7のいずれかのポリヌクレオチドを保有する組換えベクター。 9．　請求項1から3のいずれかの蛋白質ネクチン－3に対する抗体。
Applicant ※All designated countries except for US in the data before July 2012	JAPAN SCIENCE AND TECHNOLOGY AGENCY
Inventor	TAKAI, Yoshimi NAKANISHI, Hiroyuki SATO, Keiko TAKAHASHI, Kenichi
IPC(International Patent Classification)	C07K 14/78 Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin (CIG) C07K 16/18 against material from animals or humans C07K 16/28 against receptors, cell surface antigens or cell surface determinants C12N 5/10 Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells C12N 15/09 Recombinant DNA-technology C12N 15/12 Genes encoding animal proteins C12P 21/08 Monoclonal antibodies
Specified countries	National States: CA US EPO: AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR
Reference ( R and D project )	ERATO TAKAI Biotimer AREA

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Contact Information for " PROTEINS NECTIN-3 "

Japan Science and Technology Agency Department of Intellectual Property Management
URL: http://www.jst.go.jp/chizai/
E-mail:
Address: 5-3, Yonbancho, Chiyoda-ku, Tokyo, Japan , 102-8666
Fax: 81-3-5214-8476

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Contact Information for " PROTEINS NECTIN-3 "

Japan Science and Technology Agency Department of Intellectual Property Management
URL: http://www.jst.go.jp/chizai/
E-mail:
Address: 5-3, Yonbancho, Chiyoda-ku, Tokyo, Japan , 102-8666
Fax: 81-3-5214-8476

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Japanese patent	・ PROTEIN NECTIN-3

Gazette	WO 2001066736(PDF,1736KB)