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PHOTORESPONSIVE NUCLEOTIDE ANALOG CAPABLE OF PHOTOCROSSLINKING IN VISIBLE LIGHT REGION NEW

外国特許コード F190009784
整理番号 (S2017-0919-N0)
掲載日 2019年5月7日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2018JP027961
国際公開番号 WO 2019022158
国際出願日 平成30年7月25日(2018.7.25)
国際公開日 平成31年1月31日(2019.1.31)
優先権データ
  • 特願2017-144897 (2017.7.26) JP
発明の名称 (英語) PHOTORESPONSIVE NUCLEOTIDE ANALOG CAPABLE OF PHOTOCROSSLINKING IN VISIBLE LIGHT REGION NEW
発明の概要(英語) Provided are a compound represented by formula I that can be used in nucleic acid photoreaction techniques, and a photoreactive crosslinking agent comprising the compound.
従来技術、競合技術の概要(英語) BACKGROUND ART
To the basic technology of the art of molecular biology, nucleic acids and nucleic acids is cross-connected. Coupling the cross-linking the nucleic acid, for example, the hybridization of two, with the introduction of the gene, the sequence of bases used for detection, or, for example, are used in the inhibition of gene expression. Therefore, the nucleic acid of the connection and cross-linking techniques, as well as fundamental studies of molecular biology, for example, a diagnostic or therapeutic procedure in the medical field, such as therapeutic or diagnostic agents and the development and manufacturing, industrial and agricultural development such as enzymes or microorganisms in the art for use in manufacturing is very important.
As a technique for a light response of the nucleic acid, 5-cyano vinyl-deoxy-uridine of the optical coupling technique (Patent Document 1: Patent 3753938 Application, Patent Document 2: Patent Publication 3753942), 3-n structure having the modified nucleoside is a base site of the optical cross-linking techniques (Patent Document 3: Patent 4814904 Application, Patent Document 4: Patent Publication 4940311) is present.
Further, recently, the use of double-stranded nucleic acid capable of forming the construction of the various nanostructures has become possible and, in the field of nanotechnology also nucleic acid of the connection and cross-linking technique has been important. For example, Non-Patent Document 1 is, the nano-light by cross-linking DNA oligo nucleic acid-resistant sheet to provide the disclosed techniques.
  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
  • 発明者(英語)
  • FUJIMOTO,Kenzo
  • NAKAMURA,Shigetaka
国際特許分類(IPC)
指定国 National States: AE AG AL AM AO AT AU AZ BA BB BG BH BN BR BW BY BZ CA CH CL CN CO CR CU CZ DE DJ DK DM DO DZ EC EE EG ES FI GB GD GE GH GM GT HN HR HU ID IL IN IR IS JO JP KE KG KH KN KP KR KW KZ LA LC LK LR LS LU LY MA MD ME MG MK MN MW MX MY MZ NA NG NI NO NZ OM PA PE PG PH PL PT QA RO RS RU RW SA SC SD SE SG SK SL SM ST SV SY TH TJ TM TN TR TT TZ UA UG US UZ VC VN ZA ZM ZW
ARIPO: BW GH GM KE LR LS MW MZ NA RW SD SL SZ TZ UG ZM ZW
EAPO: AM AZ BY KG KZ RU TJ TM
EPO: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
OAPI: BF BJ CF CG CI CM GA GN GQ GW KM ML MR NE SN ST TD TG
※ 上記の特許・技術に関心のある方は、下記問合せ先にご相談下さい。

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