TOP > 外国特許検索 > OBSERVATION METHOD USING NON-HUMAN MAMMALIAN CEREBRAL INFARCTION MODEL, AND OBSERVATION DEVICE USING NON-HUMAN MAMMALIAN CEREBRAL INFARCTION MODEL

OBSERVATION METHOD USING NON-HUMAN MAMMALIAN CEREBRAL INFARCTION MODEL, AND OBSERVATION DEVICE USING NON-HUMAN MAMMALIAN CEREBRAL INFARCTION MODEL NEW

外国特許コード F190009791
整理番号 (S2017-0924-N0)
掲載日 2019年5月8日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2018JP030683
国際公開番号 WO 2019039438
国際出願日 平成30年8月20日(2018.8.20)
国際公開日 平成31年2月28日(2019.2.28)
優先権データ
  • 特願2017-158656 (2017.8.21) JP
発明の名称 (英語) OBSERVATION METHOD USING NON-HUMAN MAMMALIAN CEREBRAL INFARCTION MODEL, AND OBSERVATION DEVICE USING NON-HUMAN MAMMALIAN CEREBRAL INFARCTION MODEL NEW
発明の概要(英語) [Problem] To provide a method for observation by a non-human mammalian cerebral infarction model, and a device for observation by a non-human mammalian cerebral infarction model.
[Solution] The problem addressed by the present invention is solved by a method for observing a non-human mammal in a state of cerebral infarction, the method comprising performing a procedure to make the brain of an anesthetized non-human mammal observable using a remote bilateral common carotid artery occlusion model for the non-human mammal, and observing, temporally/spatially and in real time, the cerebral infarction pathology from before the onset of infarction in a cerebral blood vessel until ischemia/abnormal contraction/reperfusion through use of a two-photon laser microscope.
従来技術、競合技術の概要(英語) BACKGROUND ART
And cerebral infarction, mainly, the occlusion or stenosis of the blood vessels feeding to the brain for ischemic brain, brain tissue necrosis due to lack of oxygen and nutrients to mean a disease. In Japan, the number of patients with cerebral infarction and about 150 million, 50 million people each year about which is said to develop. Cerebral infarcts, among causes of death of Japanese that is located within position 5. And acquiring a cerebral infarction, acute phase the death of the subject, the care of a long period of time leaving the sequelae often required. Cerebral infarcts, occupies about the cause of the interrupt 3 bedridden, care, a disease associated with a great challenge in terms of well-being.
All around the world, the treatment of cerebral infarction energetically performed studies. However, even in the case of a current, a critical treatment has not been established. Conventional therapy as well as the development, since the suspected limits of the therapy, therapy based on the new concept been desired earnestly. In order to establish a new therapy, the conventional method is resolved in different ways according to conditions required for cerebral infarction. As one of the methods, exhaustive observation method in which a cerebral infarction lesions and the like. However, at present, and a cerebral infarction exhaustive observation method in which a lesion has not been established. Therefore, exhaustive observation can be performed and the new development of cerebral infarction model required for the observation method. Cerebral infarction model and exhaustive observation can be performed by establishing observation method, in the conventional observation method can be regarded the new condition cannot be found or, more reliably determine a condition such as cerebral infarction to elucidate the efficacy, treatment method can greatly help in the establishment is expected (Patent Document 1, 2).
  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • MIE UNIVERSITY
  • 発明者(英語)
  • YATA, Kenichiro
  • TOMIMOTO, Hidekazu
  • MIZOGUCHI, Akira
  • INAGAKI, Masaki
国際特許分類(IPC)
指定国 National States: AE AG AL AM AO AT AU AZ BA BB BG BH BN BR BW BY BZ CA CH CL CN CO CR CU CZ DE DJ DK DM DO DZ EC EE EG ES FI GB GD GE GH GM GT HN HR HU ID IL IN IR IS JO JP KE KG KH KN KP KR KW KZ LA LC LK LR LS LU LY MA MD ME MG MK MN MW MX MY MZ NA NG NI NO NZ OM PA PE PG PH PL PT QA RO RS RU RW SA SC SD SE SG SK SL SM ST SV SY TH TJ TM TN TR TT TZ UA UG US UZ VC VN ZA ZM ZW
ARIPO: BW GH GM KE LR LS MW MZ NA RW SD SL SZ TZ UG ZM ZW
EAPO: AM AZ BY KG KZ RU TJ TM
EPO: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
OAPI: BF BJ CF CG CI CM GA GN GQ GW KM ML MR NE SN ST TD TG
さらに詳しい情報をご要望の方は、下記「問合せ先」までお問い合わせください。未公開情報等の交換をおこなう場合は秘密保持契約を締結しての面談等にて対応しております。

PAGE TOP

close
close
close
close
close
close