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DETECTION METHOD AND DETECTION PROBE FOR COLIBACTIN AND COLIBACTIN-PRODUCING BACTERIA 新技術説明会

外国特許コード F190009799
整理番号 (S2017-0970-N0)
掲載日 2019年5月8日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2018JP031489
国際公開番号 WO 2019044736
国際出願日 平成30年8月27日(2018.8.27)
国際公開日 平成31年3月7日(2019.3.7)
優先権データ
  • 特願2017-163079 (2017.8.28) JP
発明の名称 (英語) DETECTION METHOD AND DETECTION PROBE FOR COLIBACTIN AND COLIBACTIN-PRODUCING BACTERIA 新技術説明会
発明の概要(英語) The present invention provides a detection method and detection probe for colibactin and colibactin-producing bacteria. The present invention provides, for example, the detection of myristoyl-asparagine using a tissue sample or stool sample, and a fluorescent probe which detects the enzyme activity of ClbP.
従来技術、競合技術の概要(英語) BACKGROUND ART
Koribakuchin is, known as a causative agent of a large intestine cancer, a particular group in the intestine by E. coli is produced. Koribakuchin is, to cut the DNA in an animal cell of the active thought, the patient's colon 67%, the patient's inflammatory bowel disease producing bacteria koribakuchin 40% detected from the report has been made.
For koribakuchin, myristoyl asparagine koribakuchin of the LC-MS as the structure and is detected by the reported (Non-Patent Document 1). Up to now, has been determined the chemical structure of koribakuchin not.
  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • SHIZUOKA PREFECTURE PUBLIC UNIVERSITY CORPORATION
  • 発明者(英語)
  • WATANABE KENJI
国際特許分類(IPC)
指定国 National States: AE AG AL AM AO AT AU AZ BA BB BG BH BN BR BW BY BZ CA CH CL CN CO CR CU CZ DE DJ DK DM DO DZ EC EE EG ES FI GB GD GE GH GM GT HN HR HU ID IL IN IR IS JO JP KE KG KH KN KP KR KW KZ LA LC LK LR LS LU LY MA MD ME MG MK MN MW MX MY MZ NA NG NI NO NZ OM PA PE PG PH PL PT QA RO RS RU RW SA SC SD SE SG SK SL SM ST SV SY TH TJ TM TN TR TT TZ UA UG US UZ VC VN ZA ZM ZW
ARIPO: BW GH GM KE LR LS MW MZ NA RW SD SL SZ TZ UG ZM ZW
EAPO: AM AZ BY KG KZ RU TJ TM
EPO: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
OAPI: BF BJ CF CG CI CM GA GN GQ GW KM ML MR NE SN ST TD TG

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