TOP > 外国特許検索 > MODIFIED POLYNUCLEOTIDE

MODIFIED POLYNUCLEOTIDE コモンズ

外国特許コード F190009830
整理番号 NU-2019PR-2
掲載日 2019年7月1日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2018JP030549
国際公開番号 WO 2019039403
国際出願日 平成30年8月17日(2018.8.17)
国際公開日 平成31年2月28日(2019.2.28)
優先権データ
  • 特願2017-159770 (2017.8.22) JP
発明の名称 (英語) MODIFIED POLYNUCLEOTIDE コモンズ
発明の概要(英語) The present invention addresses the problem of providing a technique for more easily transferring a polynucleotide in a less cytotoxic form into a cell. To solve this problem, provided is a polynucleotide modified with a molecule, said molecule having a structure which contains a disulfide bond and/or a thiol group.
従来技術、競合技術の概要(英語) BACKGROUND ART
In the medical field or the like, such as siRNA polynucleotide is introduced into the cells, the function thereof has been promoted the development of the technology. Polynucleotide is due to the presence of negatively charged phosphate groups and therefore, also the negatively charged cell through the membrane efficiency is low. For this reason, when a polynucleotide is introduced into the cell, a cationic lipid and a polynucleotide complex, this can be introduced into the cell, it is possible to enhance transfer efficiency (Patent Document 1) is performed.
However, when using a cationic lipid, a polynucleotide into a cell prior to the introduction of a complex work is required. Further, cationic lipid is known to be cytotoxic.
  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • NAGOYA UNIVERSITY
  • 発明者(英語)
  • ABE, Hiroshi
  • SHU, Zhaoma
国際特許分類(IPC)
指定国 National States: AE AG AL AM AO AT AU AZ BA BB BG BH BN BR BW BY BZ CA CH CL CN CO CR CU CZ DE DJ DK DM DO DZ EC EE EG ES FI GB GD GE GH GM GT HN HR HU ID IL IN IR IS JO JP KE KG KH KN KP KR KW KZ LA LC LK LR LS LU LY MA MD ME MG MK MN MW MX MY MZ NA NG NI NO NZ OM PA PE PG PH PL PT QA RO RS RU RW SA SC SD SE SG SK SL SM ST SV SY TH TJ TM TN TR TT TZ UA UG US UZ VC VN ZA ZM ZW
ARIPO: BW GH GM KE LR LS MW MZ NA RW SD SL SZ TZ UG ZM ZW
EAPO: AM AZ BY KG KZ RU TJ TM
EPO: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
OAPI: BF BJ CF CG CI CM GA GN GQ GW KM ML MR NE SN ST TD TG
名古屋大学の公開特許情報を掲載しています。ご関心のある案件がございましたら、下記まで電子メールでご連絡ください。

PAGE TOP

close
close
close
close
close
close