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PROPHYLACTIC OR THERAPEUTIC AGENT FOR PULMONARY HYPERTENSION COMPRISING MEBENDAZOLE AND/OR ITRACONAZOLE OR SALT THEREOF

外国特許コード F190009850
整理番号 (S2018-0174-N0)
掲載日 2019年7月25日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2018JP044306
国際公開番号 WO 2019111829
国際出願日 平成30年11月30日(2018.11.30)
国際公開日 令和元年6月13日(2019.6.13)
優先権データ
  • 特願2017-233034 (2017.12.5) JP
発明の名称 (英語) PROPHYLACTIC OR THERAPEUTIC AGENT FOR PULMONARY HYPERTENSION COMPRISING MEBENDAZOLE AND/OR ITRACONAZOLE OR SALT THEREOF
発明の概要(英語) The problem to be solved by the present invention is to provide a novel prophylactic or therapeutic agent for pulmonary hypertension which comprises, as an active ingredient, a compound having a previously unknown therapeutic effect on pulmonary hypertension. Provided is a prophylactic or therapeutic agent for pulmonary hypertension which comprises at least one member selected from the group consisting of mebendazole and itraconazole or a salt thereof.
従来技術、競合技術の概要(英語) BACKGROUND ART
The pulmonary hypertension, pulmonary blood from the heart to the pulmonary artery blood pressure increases and the function of the heart and lung disease and disorders, generally referred to as' high blood pressure ' is totally different from the disease condition. In addition, the high fatal pulmonary hypertension for a serious disease, the development of therapeutics that has been hurriedly carried out.
Conventional, as the treatment of pulmonary hypertension, increased vascular catheter treatment, treatment such as a surgical operation to remove the thrombus are operative, a less invasive than the desired therapy. In addition, as the medication, vasodilators or the like is known (Non-Patent Document 1 or the like), a method for treating such patients are still many that cannot, pulmonary hypertension the development of therapeutic agents is further strongly demanded.
  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • TOHOKU UNIVERSITY
  • 発明者(英語)
  • SHIMOKAWA, Hiroaki
  • SATOH, Kimio
  • OMURA, Junichi
  • KIKUCHI, Nobuhiro
  • KUROSAWA, Ryo
国際特許分類(IPC)
指定国 National States: AE AG AL AM AO AT AU AZ BA BB BG BH BN BR BW BY BZ CA CH CL CN CO CR CU CZ DE DJ DK DM DO DZ EC EE EG ES FI GB GD GE GH GM GT HN HR HU ID IL IN IR IS JO JP KE KG KH KN KP KR KW KZ LA LC LK LR LS LU LY MA MD ME MG MK MN MW MX MY MZ NA NG NI NO NZ OM PA PE PG PH PL PT QA RO RS RU RW SA SC SD SE SG SK SL SM ST SV SY TH TJ TM TN TR TT TZ UA UG US UZ VC VN ZA ZM ZW
ARIPO: BW GH GM KE LR LS MW MZ NA RW SD SL SZ TZ UG ZM ZW
EAPO: AM AZ BY KG KZ RU TJ TM
EPO: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
OAPI: BF BJ CF CG CI CM GA GN GQ GW KM ML MR NE SN ST TD TG
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