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HEMOPOIESIS-ENHANCING AGENT NEW

外国特許コード F190009957
整理番号 (S2018-0419-N0)
掲載日 2019年10月25日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2019JP007121
国際公開番号 WO 2019163994
国際出願日 平成31年2月25日(2019.2.25)
国際公開日 令和元年8月29日(2019.8.29)
優先権データ
  • 特願2018-032469 (2018.2.26) JP
発明の名称 (英語) HEMOPOIESIS-ENHANCING AGENT NEW
発明の概要(英語) The present invention addresses the problem of providing: a novel hemopoiesis-enhancing agent; and a drug for preventing or treating anemia, particularly intractable anemia, which contains the hemopoiesis-enhancing agent as an active ingredient. The present invention provides a hemopoiesis-enhancing agent which contains an S-adenosylmethionine synthetase inhibitor.
従来技術、競合技術の概要(英語) BACKGROUND ART
Conventional, such as aplastic anemia and myelodysplastic syndrome refractory anemia such as red blood cells in hematopoietic not directly effect of urging a hematopoietic formulation, chemotherapeutic or immunosuppressive therapy, a high risk of complications such as hematopoietic stem cell transplantation therapy there were. Further, the therapeutic method and the case of resistance, such as by age and there are many cases not adapt the (non-patent document 1 and 2). This is known as hematopoietic promoter formulation to renal anemia erythropoietin a certain effect is observed, an endogenous erythropoietin production already promoting blood disease anemia due to the effect cannot be expected. Therefore, the most effective treatment of the red cell transfusions and one of the cases it is often necessary, due to the long-term treatment with iron overload cost and the problem of organ failure, transfusion dependent anemia disease of the get away from the refractory and the target one.
On the other hand, S- adenosylmethionine synthetase and the MAT, the inhibitor is a cancer therapeutic agent is a candidate of the (non-patent document 3 and 4). However, S- adenosylmethionine synthetase inhibitors, hematopoietic effect is not known at all.
  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • TOHOKU UNIVERSITY
  • 発明者(英語)
  • IGARASHI, Kazuhiko
  • KATO, Hiroki
  • ISHII, Yusho
  • NGUYEN, Chi Long
  • HARIGAE, Hideo
国際特許分類(IPC)
指定国 National States: AE AG AL AM AO AT AU AZ BA BB BG BH BN BR BW BY BZ CA CH CL CN CO CR CU CZ DE DJ DK DM DO DZ EC EE EG ES FI GB GD GE GH GM GT HN HR HU ID IL IN IR IS JO JP KE KG KH KN KP KR KW KZ LA LC LK LR LS LU LY MA MD ME MG MK MN MW MX MY MZ NA NG NI NO NZ OM PA PE PG PH PL PT QA RO RS RU RW SA SC SD SE SG SK SL SM ST SV SY TH TJ TM TN TR TT TZ UA UG US UZ VC VN ZA ZM ZW
ARIPO: BW GH GM KE LR LS MW MZ NA RW SD SL SZ TZ UG ZM ZW
EAPO: AM AZ BY KG KZ RU TJ TM
EPO: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
OAPI: BF BJ CF CG CI CM GA GN GQ GW KM ML MR NE SN ST TD TG
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