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ANTITUMOR MEDICINAL COMPOSITION DERIVED FROM THUJOPSIS DOLABRATA AND INHALATION FORMULATION THEREOF NEW 新技術説明会

外国特許コード F190009973
整理番号 (H29-S13)
掲載日 2019年10月28日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2019JP006713
国際公開番号 WO 2019167823
国際出願日 平成31年2月22日(2019.2.22)
国際公開日 令和元年9月6日(2019.9.6)
優先権データ
  • 特願2018-036853 (2018.3.1) JP
発明の名称 (英語) ANTITUMOR MEDICINAL COMPOSITION DERIVED FROM THUJOPSIS DOLABRATA AND INHALATION FORMULATION THEREOF NEW 新技術説明会
発明の概要(英語) [Problem] To provide a medicinal composition derived from a natural plant that has an excellent antitumor effect with little side effect and an inhalation formulation of the same.
[Solution] A medicinal composition characterized by comprising an essential oil derived from Thujopsis dolabrata, which is a coniferous tree belonging to Thujopsis of Cupressaceae, or a volatile component of the essential oil.
従来技術、競合技術の概要(英語) BACKGROUND ART
Cypress family belonging to the genus dolabrata oak: Japanese cypress leaves are, in the japanese name dolabrata, in the name of the Thujopsis dolabrata. Oak is, unique softwood and Japan, and oak Aomori present within the prefecture Aomori, Ishikawa Prefecture noto oak is noto peninsula widely distributed is widely known.
Oak the essential extracted from oak, and is of normal, low toxicity of normal, chlamydia, MRSA, candida has antimicrobial activity against, has the effect of the preservative have been reported (Non-Patent Document 1-3). Utilizing this characteristic, are combined with the artificially dentifrice is of normal, cosmetics, hair care composition, food preservatives and the like are used. Oak the essential, other components of normal, for example β-Dolabrin, γ -Thujaplicin,4-Acetyltroplone and the like, the effect of suppressing stress (non-patent document 4) or via IgA (non-patent document 5) action immunopotentiating and the like have been reported.
Included in the anti-tumor effect of oak the essential as of normal, non-patent document 6 to the anti-tumor effect with respect to the prostate cancer cells, lung cancer cells on the non-patent document 7 with respect to the effect of inducing cell death has been disclosed. The present inventors has, other than the volatile components of the oak the essential of normal focusing is also included, as compared to the synergistic effect thereof for gastric cancer cells (non-patent document 8). The present inventors, as a result of study in further detail, and achieved the present invention.
  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • NATIONAL UNIVERSITY CORPORATION UNIVERSITY OF TOYAMA
  • 発明者(英語)
  • NAGATA Takuya
国際特許分類(IPC)
指定国 National States: AE AG AL AM AO AT AU AZ BA BB BG BH BN BR BW BY BZ CA CH CL CN CO CR CU CZ DE DJ DK DM DO DZ EC EE EG ES FI GB GD GE GH GM GT HN HR HU ID IL IN IR IS JO JP KE KG KH KN KP KR KW KZ LA LC LK LR LS LU LY MA MD ME MG MK MN MW MX MY MZ NA NG NI NO NZ OM PA PE PG PH PL PT QA RO RS RU RW SA SC SD SE SG SK SL SM ST SV SY TH TJ TM TN TR TT TZ UA UG US UZ VC VN ZA ZM ZW
ARIPO: BW GH GM KE LR LS MW MZ NA RW SD SL SZ TZ UG ZM ZW
EAPO: AM AZ BY KG KZ RU TJ TM
EPO: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
OAPI: BF BJ CF CG CI CM GA GN GQ GW KM ML MR NE SN ST TD TG
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